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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK1
All Species:
17.58
Human Site:
S442
Identified Species:
35.15
UniProt:
Q9BUB5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUB5
NP_001129025.1
465
51342
S442
K
L
S
P
P
C
K
S
R
L
A
R
R
R
A
Chimpanzee
Pan troglodytes
XP_001162271
453
49967
S430
K
L
S
P
P
C
K
S
R
L
A
R
R
R
A
Rhesus Macaque
Macaca mulatta
XP_001098645
414
46209
R395
K
S
R
L
A
R
R
R
A
Q
A
Q
A
Q
A
Dog
Lupus familis
XP_539626
415
46182
A396
S
R
L
A
R
R
R
A
L
A
Q
A
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
O08605
427
47896
A408
S
R
L
A
R
R
R
A
L
A
Q
A
G
R
S
Rat
Rattus norvegicus
Q4G050
413
46195
R394
S
K
S
R
L
A
R
R
R
A
L
A
H
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
S483
K
L
S
P
P
C
K
S
R
L
A
K
R
R
A
Frog
Xenopus laevis
Q9YGW0
418
46898
A399
K
R
R
A
Q
A
H
A
R
K
G
G
S
H
P
Zebra Danio
Brachydanio rerio
NP_001108211
459
51123
P439
V
C
S
M
R
L
S
P
P
S
N
S
R
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651986
1142
128445
Y958
Q
H
T
E
N
W
R
Y
R
T
H
H
S
Q
E
Honey Bee
Apis mellifera
XP_395927
516
58135
S488
G
L
S
P
P
S
E
S
R
L
M
Q
R
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
S489
G
L
S
P
P
G
Q
S
A
L
A
K
R
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
87.9
82.8
N.A.
85.3
82.3
N.A.
N.A.
51.5
72
68.3
N.A.
20.3
46.1
N.A.
37.7
Protein Similarity:
100
96.7
88.1
85.8
N.A.
88.5
85.3
N.A.
N.A.
63.3
79.7
76.7
N.A.
28.2
63.1
N.A.
52.4
P-Site Identity:
100
100
20
6.6
N.A.
6.6
13.3
N.A.
N.A.
93.3
13.3
20
N.A.
6.6
60
N.A.
66.6
P-Site Similarity:
100
100
40
26.6
N.A.
26.6
20
N.A.
N.A.
100
20
20
N.A.
33.3
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
9
17
0
25
17
25
42
25
9
9
50
% A
% Cys:
0
9
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
9
0
0
0
0
9
9
17
0
9
% G
% His:
0
9
0
0
0
0
9
0
0
0
9
9
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
42
9
0
0
0
0
25
0
0
9
0
17
0
0
0
% K
% Leu:
0
42
17
9
9
9
0
0
17
42
9
0
0
9
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
42
42
0
0
9
9
0
0
0
0
0
9
% P
% Gln:
9
0
0
0
9
0
9
0
0
9
17
17
0
17
0
% Q
% Arg:
0
25
17
9
25
25
42
17
59
0
0
17
50
59
0
% R
% Ser:
25
9
59
0
0
9
9
42
0
9
0
9
17
0
17
% S
% Thr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _